Deciphering the Nucleotide and RNA Binding Selectivity of the Mayaro Virus Macro Domain. Tsika AC, Melekis E, Tsatsouli SA, Papageorgiou N, Maté MJ, Canard B, Coutard B, Bentrop D, Spyroulias GA. J Mol Biol. 2019 May 31;431(12):2283-2297. doi:...
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Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.
Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells. Karantzelis N, Petropoulos M, De Marco V, Egan DA, Fish A, Christodoulou E, Will DW, Lewis JD, Perrakis A, Lygerou Z, Taraviras S. Front Pharmacol. 2022...
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage.
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage. Petropoulos M, Champeris Tsaniras S, Nikou S, Maxouri S, Dionellis VS, Kalogeropoulou A, Karamichali A, Ioannidis K, Danalatos IR, Obst M, Naumann R, Delinasios GJ,...
Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress
Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress. Kalogeropoulou A, Mougkogianni M, Iliadou M, Nikolopoulou E, Flordelis S, Kanellou A, Arbi M, Nikou S, Nieminuszczy J, Niedzwiedz W, Kardamakis D, Bravou V, Lygerou Z, Taraviras...
3D Reconstitution of the Neural Stem Cell Niche: Connecting the Dots
3D Reconstitution of the Neural Stem Cell Niche: Connecting the Dots. Ioannidis K, Angelopoulos I, Gakis G, Karantzelis N, Spyroulias GA, Lygerou Z, Taraviras S. Front Bioeng Biotechnol. 2021 Oct 28;9:705470. doi: 10.3389/fbioe.2021.705470.
A Custom Ultra-Low-Cost 3D Bioprinter Supports Cell Growth and Differentiation
A Custom Ultra-Low-Cost 3D Bioprinter Supports Cell Growth and Differentiation. Ioannidis K, Danalatos RI, Champeris Tsaniras S, Kaplani K, Lokka G, Kanellou A, Papachristou DJ, Bokias G, Lygerou Z, Taraviras S. Front Bioeng Biotechnol. 2020 Nov 4;8:580889. doi:...
Fanconi anemia proteins and genome fragility: unraveling replication defects for cancer therapy
Fanconi anemia proteins and genome fragility: unraveling replication defects for cancer therapy. Badra Fajardo N, Taraviras S, Lygerou Z. Trends Cancer. 2022 Jun;8(6):467-481. doi: 10.1016/j.trecan.2022.01.015.
Ribosomal DNA and the nucleolus at the heart of aging
Ribosomal DNA and the nucleolus at the heart of aging. Kasselimi E, Pefani DE, Taraviras S, Lygerou Z. Trends Biochem Sci. 2022 Apr;47(4):328-341. doi: 10.1016/j.tibs.2021.12.007.
In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity
In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity. Rapsomaniki MA, Maxouri S, Nathanailidou P, Garrastacho MR, Giakoumakis NN, Taraviras S, Lygeros J, Lygerou Z. NAR Genom Bioinform. 2021 Jan...